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I. J. Latham has made significant contributions to high-energy astrophysics, particularly in the study of active galactic nuclei (AGN) and very high energy (VHE) gamma-ray astronomy. Their most cited work involves multi-wavelength observations of the BL Lac object PKS 2155-304 using the High Energy Stereoscopic System (HESS), which has garnered over 100 citations. This research provided critical insights into the emission mechanisms of blazars by simultaneously observing VHE gamma rays alongside X-ray data from the Proportional Counter Array, demonstrating the power of coordinated multi-wavelength campaigns. Latham’s work has helped establish HESS as a premier instrument for studying extragalactic VHE sources and has advanced our understanding of particle acceleration processes in relativistic jets. Their contributions are foundational for researchers exploring the high-energy universe, and their observational studies continue to inform theoretical models of AGN variability and emission.