Greg Humphrey
Papers
2
Total Citations
95
H-Index
2
About
Greg Humphrey is a leading figure in microbial ecology, renowned for transforming the scalability and reliability of microbiome research. His work centers on the methodological and technical challenges of high-throughput sequencing, with a primary focus on reducing costs and contamination to enable large-scale, robust studies. Humphrey’s most impactful contribution is the development of a high-throughput, miniaturized 16S rRNA amplicon library preparation protocol, which dramatically reduces costs while preserving data integrity. This innovation, detailed in his highly cited 2018 paper (82 citations), has empowered scientists to design studies with sample sizes exceeding 10,000, democratizing access to powerful sequencing technologies. Further demonstrating his commitment to data quality, Humphrey rigorously quantified well-to-well contamination in microbiome research, providing critical frameworks for understanding and mitigating this often-overlooked source of error. His work has set new standards for experimental design in the field, ensuring that the explosion of microbiome data is both affordable and trustworthy. Through these achievements, Humphrey has become an essential architect of modern, large-scale microbial ecology.
Research Focus
Key Achievements
Top Papers
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