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About

Giorgia Antonia Simboli is a neurosurgical researcher whose work sits at the cutting edge of stereotactic and robotic neurosurgery, with a particular focus on improving the precision, safety, and feasibility of minimally invasive brain procedures. Her research centers on robot-assisted stereotactic biopsy and stereoelectroencephalography (SEEG), areas where she has made meaningful contributions to clinical practice and procedural innovation. Simboli's most influential work examines the accuracy and effectiveness of frameless registration systems combined with three-dimensional intraoperative imaging in robot-assisted brain biopsies, a study that has garnered 15 citations since its 2022 publication. Her comparative bicentric study evaluating frameless robot-assisted biopsies against conventional image-guided approaches further cements her commitment to evidence-based advancement of neurosurgical technique, accumulating 10 citations. Alongside these contributions, her investigation into intraoperative CT imaging during MRI-based robotic biopsies has added another validated layer to this evolving procedural landscape. More recently, Simboli has extended her expertise into epilepsy surgery, exploring robot-assisted SEEG for patients with drug-resistant epilepsy — a technically demanding application with significant patient impact. Across her body of work, totaling nearly 40 citations, she represents an important voice in modernizing neurosurgical workflows through robotics and real-time imaging integration.