Giedrius Lelkaitis
Papers
2
Total Citations
59
H-Index
2
About
Giedrius Lelkaitis is a leading researcher in head and neck oncology, with a particular focus on improving surgical precision through advanced imaging technologies. His work centers on the development and validation of novel intraoperative techniques for tumor margin assessment, aiming to reduce the need for adjuvant radiotherapy in patients with oropharyngeal squamous cell carcinoma (OPSCC). A key contribution is his proof-of-concept study on uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer, which demonstrated the potential for real-time tumor visualization in orthotopic xenograft models (56 citations). More recently, Lelkaitis has pioneered the use of 3D ultrasound for intraoperative margin assessment during transoral robotic surgery (TORS), showing in a pilot study that this technology can effectively distinguish tumor from healthy tissue in OPSCC patients. This work addresses a critical clinical challenge—close or positive margins—by providing surgeons with immediate feedback, potentially sparing patients from additional radiotherapy. His research bridges the gap between molecular imaging and surgical practice, offering tangible improvements in oncologic outcomes.
Research Focus
Key Achievements
Top Papers
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