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About

Enzo Mastinu is a leading researcher at the intersection of bionics, neural engineering, and prosthetics, with a career focused on restoring lost limb function through advanced human-machine interfaces. His most celebrated contribution is the development and clinical evaluation of self-contained neuromusculoskeletal arm prostheses — bone-anchored robotic limbs that enable bidirectional communication between prosthetic hands and implanted nerve and muscle electrodes. This landmark 2020 study, which followed four transhumeral amputees over three to seven years, has accumulated over 250 citations and represents a paradigm shift in how prosthetic systems integrate with the human body. Mastinu's work extends from cutting-edge clinical implants to accessible instrumentation, including open-source and low-cost bioelectric signal acquisition platforms designed to democratize prosthetics research. His contributions to osseointegrated neural interfaces, extra-neural electrode signals for individual finger control, and closed-loop prosthetic control platforms like LimbMATE demonstrate a rare breadth — spanning foundational hardware development to translational clinical science. More recently, his HANDdata dataset supports autonomous robotic grasping research. Collectively, Mastinu's work has profoundly advanced the functionality, comfort, and sensory feedback of prosthetic limbs, offering transformative quality-of-life improvements for upper limb amputees worldwide.