Elisabetta Locanto

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About

Elisabetta Locanto is a leading figure in molecular biotechnology, with her research centered on optimizing protein expression systems for biomedical and industrial applications. Her most impactful work focuses on the baculovirus expression vector system (BEVS), a cornerstone technology for producing complex recombinant proteins in insect cells. In her highly cited 2011 paper, "Optimizing the baculovirus expression vector system" (64 citations), Locanto systematically addressed key bottlenecks in BEVS, including enhancing protein yield, improving post-translational modifications, and streamlining vector design. This foundational study has become a go-to reference for researchers seeking to maximize the efficiency of insect cell-based protein production, particularly for vaccine development and therapeutic protein manufacturing. Beyond this seminal work, Locanto has contributed to advancing viral vector engineering and process optimization, bridging the gap between laboratory research and scalable biomanufacturing. Her achievements have earned her recognition as a key innovator in expression system technology, with her methodologies adopted by labs worldwide to produce high-quality proteins for structural biology, drug discovery, and gene therapy. Locanto’s work continues to drive progress in recombinant protein production, making her a vital resource for students and researchers navigating the complexities of molecular biotechnology.