Robert D. Possee

UK Centre for Ecology & Hydrology, Natural Environment Research Council

Papers

Total Citations

121

H-Index

About

Robert D. Possee is a leading virologist whose career has centered on advancing the baculovirus expression vector system (BEVS), a cornerstone technology for recombinant protein production. His major contributions lie in streamlining and optimizing this complex platform, making it more accessible and efficient for high-throughput applications. Notably, his 2008 work introduced a novel bacmid vector that eliminates the need for traditional selection steps, dramatically simplifying the process of generating recombinant baculoviruses. This innovation, detailed in a paper with 57 citations, paved the way for parallel protein production in insect cells. His 2011 review, "Optimizing the baculovirus expression vector system," has amassed 64 citations, serving as a key reference for researchers seeking to maximize yields and reliability. Possee’s work has had a profound impact on structural biology, vaccine development, and biomanufacturing, enabling the rapid production of complex eukaryotic proteins. His achievements reflect a deep understanding of viral genetics and a commitment to solving practical bottlenecks, making him a foundational figure in the field of molecular biotechnology.