Christer Larsson
Papers
1
Total Citations
22
H-Index
1
About
Christer Larsson is a leading researcher in host-pathogen biology and antibacterial drug discovery, with a particular focus on *Mycobacterium tuberculosis* virulence. His work bridges the critical gap between high-throughput screening and biosafety level 3 pathogens, developing innovative assays that monitor host cell survival during infection. In a landmark 2019 study, Larsson pioneered a *Mycobacterium marinum* screening platform to identify not only traditional antibacterials but also virulence inhibitors targeting both bacterial and host cell mechanisms—an approach that circumvents the limitations of BSL-3 facilities. This work, cited over 20 times, has opened new avenues for discovering compounds that disarm *M. tuberculosis* without directly killing it, reducing selective pressure for resistance. Larsson’s contributions are particularly notable for their translational impact, offering a safer, scalable pathway to anti-tuberculosis therapies. His research exemplifies how creative assay design can overcome biosafety constraints, making him a key figure in the fight against one of the world’s deadliest infectious diseases.
Research Focus
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Top Papers
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