Chris Brew‐Graves
University College London, Society of Interventional Radiology, Age UK
Papers
13
Total Citations
623
H-Index
10
About
Chris Brew-Graves is a clinical trials researcher whose work sits at the intersection of urological oncology and surgical innovation, with a particular focus on bladder and prostate cancer. He has made significant contributions to the design, coordination, and reporting of landmark randomised controlled trials evaluating robot-assisted surgical techniques against established open approaches. His most influential contribution is his role in the iROC trial, comparing robot-assisted radical cystectomy with intracorporeal urinary diversion to open radical cystectomy for bladder cancer. Published in *JAMA* in 2022 and accumulating over 320 citations, this work has directly shaped clinical practice by providing high-quality evidence on postoperative morbidity and recovery. A subsequent cost-effectiveness analysis further strengthened the evidence base for surgical decision-making. Brew-Graves has also been instrumental in the NeuroSAFE PROOF programme, a multi-centre randomised trial assessing whether intraoperative frozen section analysis during robot-assisted radical prostatectomy improves erectile function and urinary continence outcomes for men with prostate cancer — a question of profound quality-of-life significance. That phase 3 trial, published in 2025, adds meaningfully to the field. His collective body of work, spanning protocol development to outcomes reporting, reflects a career dedicated to generating robust surgical trial evidence that genuinely informs patient care.
Research Focus
Key Achievements
Top Papers
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