Charles Rosenblum

Merck & Co., Inc., Rahway, NJ, USA (United States)

Papers

Total Citations

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About

Charles Rosenblum is a researcher whose work centers on mitochondrial biology and its critical role in human disease. His primary contributions lie in developing innovative tools to study mitochondrial function, particularly membrane potential—a key indicator of organelle health. His most cited paper, "A Miniaturized Homogenous Assay of Mitochondrial Membrane Potential" (2011, 6 citations), introduced a streamlined, high-throughput method for assessing mitochondrial dysfunction, a hallmark of conditions like Parkinson's, Alzheimer's, type 2 diabetes, and sarcopenia. This assay enables researchers to efficiently screen for therapeutic targets aimed at restoring mitochondrial function, bridging basic science and translational medicine. Rosenblum’s work is notable for its practical impact, providing a scalable solution to a complex biological problem. By focusing on the nexus of bioenergetics and disease, he has positioned himself at the forefront of efforts to understand how mitochondrial decline drives aging and neurodegeneration. His research continues to inspire new approaches to combat these debilitating disorders, making him a valuable contributor to the field of cellular metabolism and disease pathology.