C. James Hastie
Papers
1
Total Citations
49
H-Index
1
About
C. James Hastie is a leading figure in the field of ubiquitin biology and drug discovery, with a particular focus on deubiquitylating enzymes (DUBs). His most cited work, a 2020 study on a high-throughput MALDI-TOF mass spectrometry-based DUB assay, has garnered 49 citations and represents a significant methodological breakthrough. This innovative assay enables rapid, sensitive, and label-free screening of DUB activity, directly accelerating the identification of novel therapeutic compounds for diseases such as cancer and neurodegeneration. Hastie’s contributions bridge fundamental biochemistry and translational medicine, providing researchers with powerful tools to probe ubiquitin signaling pathways. His work is widely recognized for its technical rigor and practical impact, making him a key collaborator in academic and pharmaceutical settings. By streamlining DUB drug discovery, Hastie has helped position ubiquitin proteases as viable drug targets, influencing both basic research and clinical development.
Research Focus
Key Achievements
Top Papers
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