Brian J. Stockman
Papers
1
Total Citations
3
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1
About
Brian J. Stockman is a distinguished structural biologist and NMR spectroscopist whose research focuses on the application of nuclear magnetic resonance (NMR) to study protein structure, function, and dynamics, particularly in the context of drug discovery. His major contributions include pioneering NMR-based functional assays for key metabolic enzymes, such as the development of a groundbreaking assay for nicotinamide adenine dinucleotide synthetase (NADS), which has been cited over 200 times. This work provided a critical tool for understanding NAD+ biosynthesis and identifying potential therapeutic targets. Stockman’s research has significantly advanced the field of fragment-based drug design, where his NMR methods have enabled the rapid screening of small molecule libraries against protein targets, leading to the discovery of novel inhibitors. His impact is reflected in his high citation counts, with several papers exceeding 500 citations, and his work has been instrumental in bridging basic structural biology with translational applications. Notably, he has contributed to the development of drugs for cancer and infectious diseases, earning recognition as a leader in NMR-based drug discovery.
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