Alexander S. McColl
Papers
1
Total Citations
3
H-Index
1
About
Alexander S. McColl is a biochemist whose work has centered on the development of innovative functional assays for key metabolic enzymes. His most recognized contribution is the creation of a nuclear magnetic resonance (NMR)-based functional assay for nicotinamide adenine dinucleotide (NAD+) synthetase, a critical enzyme in cellular energy metabolism and redox regulation. This methodological advance, detailed in his 2007 paper, provided a novel, non-destructive approach to studying enzyme kinetics and inhibitor interactions, offering a valuable tool for researchers investigating metabolic pathways and potential therapeutic targets. While his work has accrued a modest citation count of 3, its significance lies in the niche application of NMR to probe NAD+ biosynthesis, a process central to cellular health and disease. McColl's research exemplifies a focused, technique-driven approach to enzymology, contributing to the broader understanding of how metabolic enzymes can be studied in real time. His work remains a reference point for those exploring NMR-based assays in metabolic biochemistry.
Research Focus
Key Achievements
Top Papers
- 1