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About

Brian Ayers is a pioneering researcher at the intersection of soft robotics and cardiovascular medicine, whose work is redefining how we model, treat, and interact with the heart. His primary research areas include biohybrid cardiac simulators, minimally invasive surgical tools, and targeted drug delivery systems. Ayers’s most impactful contribution is the development of the "Robotic Right Ventricle," a biohybrid platform that accurately mimics right ventricular biomechanics and hemodynamics—including free wall, septal, and valve motion—under both healthy and diseased conditions. This work, cited 27 times since 2023, provides a revolutionary testbed for developing RV-focused interventions and devices. He also created the "SmartSleeve," a sutureless soft robotic epicardial device that enables switchable, on-off drug delivery in response to real-time ECG sensing (11 citations), addressing a critical challenge in controlled epicardial therapy. More recently, Ayers introduced a beating-heart procedure with soft robotic guidance for cardiac resynchronization therapy (6 citations), and he has integrated soft robotics with computational models to study left atrial hemodynamics in sinus rhythm and atrial fibrillation. His work is notable for bridging engineering and clinical cardiology, offering tangible solutions for device testing and patient-specific treatment.