Bettina Halder
Papers
1
Total Citations
22
H-Index
1
About
Bettina Halder is a researcher whose work sits at the critical intersection of biopharmaceutical development and advanced imaging technology. Her primary research focus is the characterization of protein aggregates, particularly monoclonal antibodies (mAbs), which are vital for ensuring the safety and efficacy of biologic drugs. Halder’s most notable contribution is her pioneering use of automated fluorescence microscopy imaging for the high-throughput analysis of sub-visible mAb aggregate particles. Her landmark 2017 paper on this technique, which has garnered 22 citations, introduced a more efficient and detailed method for detecting and classifying these potentially immunogenic particles, moving beyond traditional light obscuration methods. This work provides pharmaceutical scientists with a powerful tool for early-stage formulation screening and quality control. By enabling a deeper understanding of aggregate morphology and size distribution, Halder’s research directly supports the development of safer, more stable therapeutic proteins, making her a key contributor to the field of biophysical characterization in the pharmaceutical industry.
Research Focus
Key Achievements
Top Papers
- 1