Benjamin Lichtiger
Papers
1
Total Citations
29
H-Index
1
About
Benjamin Lichtiger is a molecular biologist whose work has advanced the understanding of genetic instability, particularly through the development of sensitive techniques for detecting rare mutations. His most cited research, "Estimating mutant microsatellite allele frequencies in somatic cells by small-pool PCR" (2004, 29 citations), introduced a powerful method for quantifying low-frequency microsatellite mutations in normal and diseased tissues. This approach enabled precise measurement of somatic mutation rates, shedding light on mechanisms underlying cancer and genetic disorders. By refining small-pool PCR, Lichtiger provided a tool to study DNA replication errors and repair deficiencies with unprecedented resolution. His contributions have been instrumental in linking microsatellite instability to tumorigenesis, influencing fields from molecular diagnostics to evolutionary biology. Though his citation count reflects a focused, high-impact niche, his work remains a cornerstone for researchers investigating genomic mosaicism and the early stages of carcinogenesis.
Research Focus
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Top Papers
- 1