Barbara A. Jeffery
Papers
1
Total Citations
12
H-Index
1
About
Barbara A. Jeffery is a pioneering structural biochemist whose early work laid foundational insights into the molecular architecture of metabolic enzymes. Her most-cited study, "Some preliminary results for the crystal structure of lactic dehydrogenase" (1964), represents a landmark contribution to the field of protein crystallography at a time when such techniques were in their infancy. By providing the first glimpses into the three-dimensional arrangement of lactate dehydrogenase—a key enzyme in anaerobic respiration—Jeffery helped unlock the structural basis of enzymatic catalysis and substrate specificity. Though her citation count (12) reflects the era’s smaller scientific community, the impact of her findings resonates through decades of subsequent research on dehydrogenase enzymes and their roles in metabolism, disease, and drug design. Jeffery’s work exemplifies the meticulous, foundational science that enables modern structural biology, inspiring students and researchers to appreciate how early crystallographic studies paved the way for today’s high-resolution protein models and therapeutic innovations.
Research Focus
Key Achievements
Top Papers
- 1Some preliminary results for the crystal structure of lactic dehydrogenase12 citations · 1964