Arne Mehrkens
Papers
1
Total Citations
49
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1
About
Arne Mehrkens is a leading researcher in the field of intervertebral disc (IVD) degeneration, with a primary focus on the biological and biomechanical mechanisms underlying degenerative disc disease. His most cited work, "The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc" (2015), has garnered 49 citations, establishing a foundational understanding of how species-specific differences—particularly between chondrodystrophic and non-chondrodystrophic canines—influence disc pathology. In this study, Mehrkens employed cutting-edge iTRAQ proteomic methods to quantify the secretome of the nucleus pulposus, linking molecular profiles to biomechanical properties. His contributions have advanced the translational relevance of canine models for human disc degeneration, offering insights into early diagnostic markers and potential therapeutic targets. Mehrkens’ work is notable for bridging proteomics and biomechanics, providing a comprehensive view of disc health and disease. His research continues to inform orthopedic and neurosurgical approaches to spinal disorders, making him a key figure in the study of degenerative disc disease and its biological underpinnings.
Research Focus
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Top Papers
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