Arne Helland

Norwegian University of Science and Technology

Papers

Total Citations

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About

Arne Helland is a researcher specializing in bioanalytical chemistry and clinical pharmacology, with a focus on the precise quantification of pharmaceutical compounds in biological matrices. His work is particularly impactful in the field of therapeutic drug monitoring, where accurate measurement of drug concentrations is critical for optimizing patient treatment. Helland’s most cited paper, "Quantification of 21 antihypertensive drugs in serum using UHPLC-MS/MS" (2018, 25 citations), exemplifies his contribution to developing robust, high-throughput analytical methods. This study introduced a validated ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) technique capable of simultaneously measuring a broad panel of antihypertensive agents, enabling efficient and reliable monitoring of polypharmacy in patients with hypertension. By streamlining the analysis of multiple drugs in a single run, Helland’s work reduces sample volume, time, and cost, directly benefiting clinical laboratories and research settings. His research underscores the importance of analytical rigor in personalized medicine, and his methods are widely adopted for pharmacokinetic studies and routine clinical assays. Helland’s dedication to advancing bioanalytical techniques continues to support safer and more effective pharmacotherapy.