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About

Andrej Alfirevic is a clinical researcher and anesthesiologist whose work has significantly advanced the field of regional anesthesia in cardiac and thoracic surgery. His research is primarily focused on fascial plane nerve blocks — particularly serratus anterior and pectoralis plane blocks — as innovative alternatives to opioid-based pain management in minimally invasive procedures. Alfirevic has been at the forefront of evaluating these techniques in complex surgical contexts, including robotically assisted mitral valve repair and minimally invasive thoracic surgery, where effective pain control is critical to preserving pulmonary function and improving patient recovery. His most impactful contribution, a randomized clinical trial investigating serratus anterior and pectoralis plane blocks in mitral valve surgery, has garnered 33 citations since 2023, reflecting rapid uptake in the anesthesia community. Subsequent work exploring the use of liposomal bupivacaine to extend analgesic duration, as well as pharmacokinetic sub-studies examining blood bupivacaine concentrations, demonstrates his commitment to both clinical efficacy and patient safety. His engagement with peer commentary further underscores his role as a thought leader in chest wall regional anesthesia, helping shape evolving best practices for opioid-sparing perioperative care.