Anders Heding
Papers
2
Total Citations
81
H-Index
2
About
Anders Heding is a researcher whose work bridges molecular endocrinology and receptor pharmacology, with a particular focus on the biophysical characterization of peptide–receptor and binding-protein interactions. His most cited contribution, a 1996 study on the binding of insulin-like growth factors (IGF-I and IGF-II) to IGF-binding protein-3 (IGFBP-3), remains a foundational reference in the field. Using biosensor technology, Heding precisely measured the affinities of these interactions, providing critical data that clarified how IGFs are sequestered in the circulation. This work has accumulated 65 citations and continues to inform studies on growth factor regulation and therapeutic analog design. In a second notable study (2002), Heding introduced a novel microplate-based method for real-time measurement of Ca²⁺ signaling via the human NK1 receptor. By leveraging automated fluorescence detection, he demonstrated a high-throughput approach to studying G-protein-coupled receptor activation, earning 16 citations for its methodological innovation. Together, Heding’s research exemplifies a career dedicated to refining how we quantify and understand key signaling events—from growth factor bioavailability to neurotransmitter receptor dynamics—offering tools and insights that have shaped subsequent experimental design in both academia and drug discovery.
Research Focus
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Top Papers
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