Alessio Bartocci
Université Claude Bernard Lyon 1, École Normale Supérieure de Lyon
Papers
2
Total Citations
15
H-Index
2
About
Alessio Bartocci is a structural biologist whose research focuses on advancing protein crystallography through innovative chemical additives. His key work centers on the use of lanthanide-based complexes—specifically [Eu(DPA)₃]³⁻ and Tb-Xo4—as powerful auxiliaries for biocrystallography. Bartocci’s major contribution lies in systematically analyzing how commercial crystallization kit compositions and the presence of divalent cations influence the efficiency of these lanthanide additives. His 2021 study, which has garnered 12 citations, reveals critical insights into the role of tris-dipicolinate complexes in enhancing crystal formation and diffraction quality. This work addresses a fundamental challenge in structural biology: obtaining well-diffracting protein crystals for X-ray analysis. By elucidating the interplay between lanthanide additives and crystallization conditions, Bartocci’s research provides practical guidelines for improving crystallization success rates. His findings are particularly valuable for researchers working on challenging protein targets, offering a systematic approach to optimizing crystallization screens. Bartocci’s contributions bridge the gap between coordination chemistry and structural biology, demonstrating how carefully designed metal complexes can serve as versatile tools for advancing our understanding of macromolecular structures.
Research Focus
Key Achievements
Top Papers
- 1
- 2