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About

Alessandro de Sire is a leading researcher in neurorehabilitation and robotic-assisted therapy, with a primary focus on restoring motor function after neurological injury. His major contributions lie in evaluating the efficacy of robotic exoskeletons and end-effector devices for gait and upper limb recovery, particularly in stroke survivors and patients with cervical spinal cord injury. His highly cited 2021 systematic review on robotic exoskeletons for subacute stroke gait rehabilitation (119 citations) is a foundational work in the field, demonstrating significant improvements in mobility and independence. He has also advanced comparative analyses of exoskeleton versus end-effector hand therapy (63 citations), providing critical evidence for clinical decision-making. More recently, de Sire has explored the integration of socially assistive robots in rehabilitation settings and combined approaches for spasticity management using botulinum toxin. His work on task-oriented robotic rehabilitation for post-ICU obese patients highlights his commitment to addressing complex, underserved populations. With a growing citation impact and a focus on translating technology into practical, patient-centered outcomes, de Sire is shaping the future of neurorehabilitation robotics.