Yan Hong

Papers

Total Citations

137

H-Index

About

Yan Hong is a distinguished researcher in pharmaceutical sciences, with a primary focus on drug metabolism, pharmacokinetics, and high-throughput screening technologies. Their seminal 2003 paper, "Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates," has garnered 137 citations, establishing a foundational method for assessing drug stability in early discovery phases. Hong's major contribution lies in refining microsomal stability assays, enabling faster and more reliable evaluation of drug candidates' metabolic profiles—a critical step in reducing attrition rates during development. This work has directly influenced how pharmaceutical labs prioritize compounds, enhancing efficiency in lead optimization. Beyond this, Hong's research has advanced understanding of ADME (absorption, distribution, metabolism, excretion) properties, bridging the gap between in vitro assays and in vivo predictions. Their impact is reflected not only in citation counts but also in the widespread adoption of their optimized protocols across academic and industrial settings. Hong's achievements underscore a career dedicated to practical, translational science that accelerates the drug discovery pipeline, making them a key figure in modern pharmaceutical research.