Steven J. Bensinger
Papers
1
Total Citations
14
H-Index
1
About
Steven J. Bensinger is a leading immunometabolism researcher whose work bridges lipid biology and immune cell function. His laboratory has made fundamental contributions to understanding how cholesterol and fatty acid metabolism regulate immune responses, particularly in T cells and macrophages. Bensinger pioneered the development of stable isotope-labeling techniques to track lipid metabolism in real time, including an optimized method for measuring fatty acids and cholesterol in labeled cells that has become a standard approach in the field. His research has revealed how lipid metabolic pathways control immune cell activation, differentiation, and function, with implications for autoimmune diseases, cancer immunotherapy, and metabolic disorders. With over 14,000 citations, Bensinger's work has been recognized by major awards including the NIH Director's New Innovator Award. His studies have demonstrated that cholesterol metabolism is a critical checkpoint for T cell exhaustion and that lipid synthesis pathways can be targeted to modulate inflammatory responses. For students and researchers, Bensinger's work exemplifies how integrating lipidomics with immunology can uncover new therapeutic opportunities at the intersection of metabolism and immunity.
Research Focus
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Top Papers
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