Serge Cremers

Leiden University Medical Center

Papers

1

Total Citations

19

H-Index

1

About

Serge Cremers is a clinical pharmacologist and analytical chemist whose work has significantly advanced the measurement and understanding of bisphosphonates—drugs critical for treating bone diseases like osteoporosis. His key research areas include bioanalytical chemistry, pharmacokinetics, and therapeutic drug monitoring, with a particular focus on developing sensitive methods to quantify these challenging compounds in biological fluids. Cremers’s most cited work, a 2000 paper on the semi-automatic liquid chromatographic analysis of olpadronate, introduced a novel derivatization technique using (9-fluorenylmethyl)chloroformate. This method enabled reliable detection of the drug in urine and serum, overcoming previous analytical hurdles and providing a foundation for future pharmacokinetic studies. With 19 citations, this contribution has been instrumental for researchers and clinicians seeking to optimize bisphosphonate therapy. Beyond this, Cremers has made notable contributions to the field of clinical pharmacology, including work on drug–drug interactions and personalized medicine. His expertise in bridging analytical chemistry with clinical application has made him a respected figure in bone metabolism research, helping to ensure that patients receive safer, more effective treatments.

Research Focus

Key Achievements

1
H-Index
1
Papers
19
Total Citations
19
Avg Citations/Paper
🏆 Most Cited Paper
Semi-automatic liquid chromatographic analysis of olpadronate in urine and serum using derivatization with (9-fluorenylmethyl)chloroformate
19 citations · 2000
📈 Most Prolific Year: 2000 (1 Papers)
🤝 Key Collaborators: 4
🏛 Institutions: Leiden University Medical Center

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
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