Sandra Jeudy
Papers
1
Total Citations
20
H-Index
1
About
Sandra Jeudy is a structural biologist whose research focuses on the discovery of novel antibacterial targets through the lens of bacterial protein structure and function. Her major contributions lie in the field of structural genomics, where she employs X-ray crystallography to elucidate the three-dimensional architecture of proteins that are essential to bacterial pathogens. Her most cited work, the 2005 paper detailing the crystal structure of *Escherichia coli* DkgA, a broad-specificity aldo-keto reductase, has garnered 20 citations and exemplifies her approach. This study was conducted as part of the Structural and Functional Genomics program (BIGS), a large-scale initiative aimed at identifying new antibacterial targets among proteins that are both ubiquitous in bacterial pathogens and exhibit strong sequence conservation. By solving the structure of DkgA, Jeudy provided critical insights into a potential target for novel antibiotics, contributing to the foundational knowledge necessary for combating drug-resistant infections. Her work represents a key intersection of structural biology and applied microbiology, offering a pathway toward the rational design of next-generation antimicrobial agents.
Research Focus
Key Achievements
Top Papers
- 1