Peter Kierulf
Papers
3
Total Citations
148
H-Index
3
About
Peter Kierulf is a distinguished researcher whose work bridges molecular diagnostics, pharmacogenomics, and clinical microbiology. His key research areas include the molecular quantification of infectious pathogens, genetic determinants of drug response, and methodological innovations in gene expression analysis from whole blood. Kierulf’s most impactful contribution is his pioneering use of robotized DNA isolation combined with real-time PCR to quantify *Neisseria meningitidis* DNA in plasma and cerebrospinal fluid from patients with systemic meningococcal disease (108 citations). This work demonstrated a close correlation between bacterial DNA levels and lipopolysaccharides, offering a rapid, sensitive diagnostic tool that has influenced infectious disease management. He also advanced pharmacogenomics by studying how *CYP2C9* and *VKORC1* genotypes affect warfarin dose and INR in myocardial infarction patients, contributing to personalized anticoagulation therapy. Additionally, his methodological work on quantifying mRNA changes from frozen whole blood (18 citations) established robust protocols for gene expression studies, with implications for biomarker discovery. Kierulf’s research is characterized by its translational impact, combining automation and molecular biology to improve clinical diagnostics and therapeutic monitoring.
Research Focus
Key Achievements
Top Papers
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