Kari Bente Foss Haug
Papers
3
Total Citations
148
H-Index
3
About
Kari Bente Foss Haug is a molecular biologist whose pioneering work bridges infectious disease diagnostics and pharmacogenomics. Her most influential contribution, a 2004 study with 108 citations, revolutionized the detection of systemic meningococcal disease by combining robotized DNA isolation with real-time PCR. By targeting the *Neisseria meningitidis*-specific capsular transport A gene, she demonstrated a rapid, sensitive method to quantify bacterial DNA in plasma and cerebrospinal fluid, revealing a close correlation with lipopolysaccharide levels—a critical advance for early diagnosis and treatment of this life-threatening infection. Haug also made significant strides in personalized medicine. Her 2008 study on warfarin therapy in myocardial infarction patients (22 citations) explored how genetic variants of *CYP2C9* and *VKORC1* influence drug dose and INR response, contributing to the growing field of genotype-guided anticoagulation. Additionally, her 2007 work (18 citations) established a robotic method for RNA isolation from frozen whole blood, enabling reliable gene expression analysis of LPS-regulated transcripts. This methodological innovation has implications for studying immune responses in clinical settings. Haug’s research exemplifies how molecular techniques can transform both acute care and chronic disease management.
Research Focus
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Top Papers
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