Peggy J. Stupca
Papers
1
Total Citations
21
H-Index
1
About
Peggy J. Stupca’s research has centered on the critical intersection of prenatal genetics and laboratory methodology, with a particular focus on improving the accuracy of amniotic fluid analysis. Her most cited work, a 1992 study involving 4,309 consecutive amniotic fluid specimens, systematically evaluated the clinical definitions of pseudomosaicism, true mosaicism, and maternal cell contamination when using in situ culture and robotic harvesting. By prospectively testing these classifications, Stupca provided essential guidelines that helped cytogeneticists distinguish benign culture artifacts from genuine fetal abnormalities, directly reducing diagnostic errors in prenatal testing. This foundational study has accumulated 21 citations, reflecting its lasting influence on laboratory protocols. Her contributions have been particularly valuable in an era when robotic automation was first being introduced to cytogenetics, helping to validate these technologies for clinical use. Through her meticulous work, Stupca has helped shape the standards that ensure more reliable prenatal diagnoses, benefiting both clinicians and the families they counsel.
Research Focus
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Top Papers
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