P.L. Jager
Papers
1
Total Citations
21
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1
About
Dr. P.L. Jager is a pioneer in the development of radiochemistry for positron emission tomography (PET) imaging, with a primary focus on creating novel tracers for neuroendocrine tumors (NETs). Their most significant contribution is the development of a reliable, remote-controlled synthesis of β-[¹¹C]-5-hydroxy-L-tryptophan (5-HTP), a critical PET tracer that visualizes the specific metabolic activity of NETs. This work, published in 2006 and cited 21 times, addressed the technical challenge of producing carbon-11 labeled 5-HTP on a Zymark robotic system, enabling more precise staging of neuroendocrine tumors. By facilitating the automated and reproducible synthesis of this tracer, Dr. Jager’s research has advanced the clinical utility of PET imaging for NETs, complementing other tracers like [¹⁸F]FDOPA. Their work has had a lasting impact on the field of nuclear medicine and radiochemistry, providing a foundation for improved diagnostic accuracy in oncology. Dr. Jager’s contributions exemplify the critical role of radiochemical innovation in translating molecular imaging from bench to bedside.
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