Nicolas Gompel
Papers
1
Total Citations
28
H-Index
1
About
Nicolas Gompel is a leading evolutionary and developmental biologist whose research bridges genomics, gene regulation, and the evolution of morphological diversity. His major contributions center on understanding how cis-regulatory elements and core promoters shape gene expression, particularly in Drosophila. In his landmark 2022 study, Gompel conducted a large-scale, systematic dissection of the Drosophila core promoter using synthetic promoters, revealing how sequence architecture "computes" expression levels—a pivotal advance in decoding the regulatory logic of metazoan genomes. His work has garnered over 28 citations for this study alone, reflecting its impact on the fields of functional genomics and evo-devo. Beyond this, Gompel is renowned for his pioneering research on the genetic basis of pigmentation pattern evolution in fruit flies, demonstrating how modular enhancer changes drive adaptive traits. His integrative approach—combining bioinformatics, synthetic biology, and transgenic assays—has set new standards for dissecting promoter function. A professor at the University of California, San Diego, Gompel’s research continues to illuminate the fundamental principles by which genomes encode complex developmental programs, making him a key figure for students and researchers interested in the intersection of genomics, evolution, and gene regulation.
Research Focus
Key Achievements
Top Papers
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