Mariam Museridze
Papers
1
Total Citations
28
H-Index
1
About
Mariam Museridze is a molecular biologist whose research centers on the regulatory logic of gene expression, with a particular focus on the core promoter—the critical hub where transcription is initiated. Her major contribution lies in systematically dissecting how core promoter sequences "compute" gene expression levels in metazoans. In her landmark 2022 study, which has garnered 28 citations, Museridze conducted a large-scale, genome-wide bioinformatic analysis in *Drosophila*, followed by a comprehensive structure-function analysis using synthetic promoters. This work revealed fundamental principles of how core promoter architecture dictates transcriptional output, bridging the gap between DNA sequence and quantitative expression. By combining computational genomics with synthetic biology, she has provided a powerful framework for understanding the regulatory code embedded in promoter regions. Her findings have significant implications for both basic developmental biology and synthetic gene circuit design. Museridze’s research exemplifies how systematic, high-throughput approaches can unravel the complex grammar of gene regulation, making her a rising voice in the field of transcriptional control.
Research Focus
Key Achievements
Top Papers
- 1