Mark G. Erlander
Papers
2
Total Citations
387
H-Index
2
About
Mark G. Erlander is a pioneering figure in genomics and transcriptomics, best known for his foundational work in developing high-throughput technologies for comprehensive gene expression analysis. His major contributions include the creation of the first viral DNA microarray, specifically for human cytomegalovirus (HCMV), which enabled simultaneous expression profiling of nearly all open reading frames. This landmark study, published in 1999, has garnered over 257 citations and revolutionized the study of viral gene regulation and drug sensitivity. Erlander also invented TOGA (Total Gene Expression Analysis), an automated parsing technology that systematically displays and quantifies nearly all expressed genes. This innovative method, cited more than 130 times, provided an early solution for global transcriptome profiling before the advent of next-generation sequencing. His work has had a lasting impact on functional genomics, enabling researchers to dissect complex biological pathways and identify therapeutic targets. Erlander’s contributions remain essential reading for students and scientists in molecular biology, virology, and bioinformatics, exemplifying how clever technological design can unlock profound biological insights.
Research Focus
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