Marc Noverraz
Papers
1
Total Citations
170
H-Index
1
About
Marc Noverraz is a leading figure in bioprocess engineering, whose work has fundamentally advanced the understanding and optimization of protein purification. His primary research focuses on the thermodynamics and kinetics of protein adsorption, particularly on complex mixed-mode chromatographic resins. Noverraz’s most impactful contribution is his pioneering development of high-throughput experimental methods for isotherm determination, which he combined with rigorous thermodynamic modeling. This approach, detailed in his highly cited 2010 paper (170 citations), allows for the rapid, systematic prediction of protein binding behavior under various conditions, replacing slow, trial-and-error methods. By enabling precise modeling of adsorption equilibria, his work has significantly accelerated the design of efficient downstream processing steps for therapeutic proteins. This has profound implications for reducing the cost and time of biopharmaceutical manufacturing. Noverraz’s research stands as a cornerstone for modern, data-driven bioprocess development, bridging the gap between fundamental physical chemistry and industrial application.
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