Lidia Nieto‐Rodriguez
Papers
1
Total Citations
43
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1
About
Dr. Lidia Nieto-Rodriguez is a leading figure in synthetic organic chemistry, renowned for her transformative work in peptide synthesis methodology. Her research focuses on the development and mechanistic understanding of novel coupling reagents, with a particular emphasis on the Oxyma scaffold. Her most impactful contribution is her seminal 2013 study on COMU, a uronium salt that revolutionized peptide bond formation. This highly cited work (43 citations) systematically delineated the scope and limitations of COMU, establishing it as a groundbreaking alternative to classical reagents like HATU and HBTU. By demonstrating COMU’s superior efficiency, reduced racemization, and enhanced safety profile, Dr. Nieto-Rodriguez provided the scientific community with a powerful, practical tool for peptide acyl transfer. Her research has directly influenced both academic laboratories and industrial peptide synthesis, accelerating drug discovery and bioconjugation. Through her rigorous analysis of reagent performance, she has set a new standard for innovation in the field, cementing her legacy as a key architect of modern peptide chemistry.
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Top Papers
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