Jane B. Trepel
Papers
2
Total Citations
24
H-Index
2
About
Dr. Jane B. Trepel is a distinguished cancer researcher whose work focuses on the molecular mechanisms driving tumor progression and therapeutic resistance, with a particular emphasis on prostate and esophageal cancers. Her research integrates cutting-edge approaches in liquid biopsy, metabolomics, and functional profiling to advance precision oncology. In a pivotal 2015 study (16 citations), Dr. Trepel investigated whether robotic-assisted laparoscopic radical prostatectomy alters intraoperative levels of circulating tumor cells (CTCs), providing critical insights into the biological impact of surgical manipulation on cancer dissemination. More recently, her 2018 work (8 citations) pioneered the application of metabolomic and BH3 profiling in esophageal cancers, developing novel assessment methods to predict responses to neoadjuvant chemoradiotherapy. This research addresses the urgent need for biomarkers that can identify patients most likely to benefit from treatment, given the rising incidence of esophageal cancer. Dr. Trepel’s contributions are shaping how clinicians evaluate tumor biology in real time, bridging the gap between laboratory discovery and clinical decision-making. Her innovative use of functional assays and metabolic signatures underscores her commitment to personalizing cancer therapy and improving outcomes for patients with aggressive malignancies.
Research Focus
Key Achievements
Top Papers
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