Hans Adolfsson
Papers
1
Total Citations
31
H-Index
1
About
Hans Adolfsson is a leading figure in asymmetric catalysis, with a particular focus on developing efficient and selective methods for synthesizing chiral molecules. His research centers on the design of novel ligand libraries and their application in transition metal-catalyzed transformations, most notably asymmetric transfer hydrogenation. A key contribution is his work on high-throughput screening of catalyst libraries, exemplified by his 2012 study (31 citations) that identified highly effective ruthenium and rhodium catalysts for reducing heteroaromatic ketones. This work enabled the formal syntheses of the important pharmaceuticals (R)-fluoxetine and (S)-duloxetine, demonstrating the practical impact of his methodology. By systematically combining amino acid-based ligands with metal precursors, Adolfsson has created powerful tools for accessing enantiomerically pure compounds, a critical need in drug discovery and fine chemical synthesis. His research is widely recognized for its innovation and utility, providing chemists with robust, scalable solutions for asymmetric synthesis.
Research Focus
Key Achievements
Top Papers
- 1