Grant Mathison

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About

Grant Mathison is a leading clinical researcher in head and neck oncology, with a primary focus on optimizing treatment outcomes for oropharyngeal squamous cell carcinoma (OPSCC). His most influential work, the 2016 study "Survival and Gastrostomy Prevalence in Patients With Oropharyngeal Cancer Treated With Transoral Robotic Surgery vs Chemoradiotherapy," has garnered 68 citations and fundamentally shaped the debate between surgical and non-surgical treatment paradigms. Mathison’s major contribution lies in rigorously comparing functional outcomes—specifically gastrostomy tube dependence—and survival between transoral robotic surgery (TORS)-based approaches and chemoradiotherapy. By demonstrating that TORS can achieve comparable oncologic control while potentially reducing long-term swallowing morbidity, his research has empowered clinicians to make more personalized, function-preserving treatment decisions. This work is particularly notable for addressing the critical challenge of treatment-related toxicity in a disease with rising incidence. Mathison’s scholarship provides essential evidence for multidisciplinary tumor boards, helping to balance cure rates with quality of life. His findings continue to influence clinical guidelines and inspire further investigation into minimally invasive surgical techniques for head and neck cancers.