Fernando Unda
Papers
1
Total Citations
87
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1
About
Fernando Unda's research centers on the molecular mechanisms of craniofacial and dental development, with a particular focus on the role of transcription factors in epithelial-mesenchymal interactions. His most cited work, a 2003 study on the Krüppel-like factor Epiprofin, has garnered 87 citations and represents a foundational contribution to the field. In this landmark paper, Unda and his team identified a novel cDNA clone for epiprofin, expressed preferentially in the epithelium of developing teeth, hair follicles, and limb buds. By employing DNA microarrays on an embryonic mouse molar cDNA library, they demonstrated that epiprofin promotes cell proliferation, establishing its critical function in organogenesis. This discovery has significantly advanced our understanding of how epithelial signaling governs tissue development and regeneration. Unda’s work is widely recognized for its impact on developmental biology and regenerative dentistry, providing key insights into the genetic pathways that orchestrate tooth and hair formation. His contributions continue to inspire research into therapeutic applications for congenital anomalies and tissue engineering.
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