Susana de-Vega
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1
Total Citations
87
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1
About
Susana de-Vega is a leading developmental biologist whose research focuses on the molecular mechanisms governing organogenesis, with a particular emphasis on tooth and hair follicle development. Her major contributions center on the discovery and characterization of Epiprofin (also known as Sp6), a Krüppel-like factor transcription factor that plays a critical role in epithelial cell proliferation and differentiation. In her seminal 2003 paper, which has garnered 87 citations, de-Vega identified the Epiprofin cDNA clone through differential hybridization of DNA microarrays from embryonic mouse molar libraries, demonstrating its preferential expression in developing teeth, hair follicles, and limb buds. This foundational work established Epiprofin as a key regulator of epithelial development and has paved the way for subsequent studies on its role in craniofacial and skin morphogenesis. Her research has significantly advanced our understanding of how transcription factors orchestrate complex tissue formation, with implications for regenerative medicine and congenital anomaly research. De-Vega’s work continues to inspire investigations into the genetic pathways controlling epithelial-mesenchymal interactions during development.
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