Dominique Mathieu

About

Dominique Mathieu is a leading clinical researcher in radiation oncology, whose work has fundamentally advanced the precision and patient-centered outcomes of stereotactic ablative radiotherapy (SABR) for early-stage lung cancer. Her research focuses on two critical pillars of modern radiotherapy: optimizing treatment planning accuracy and rigorously measuring long-term patient quality of life. Mathieu’s landmark 2015 study, cited 24 times, provided crucial evidence that robotic SABR not only achieves high tumor control but also preserves excellent long-term quality of life for early-stage non-small cell lung cancer patients—a finding that directly supports the use of this non-invasive technique over more aggressive surgical options. In her foundational 2014 work on breath-hold CT for treatment planning, Mathieu demonstrated a novel method to improve tumor targeting accuracy, reducing the risk of damage to healthy lung tissue. Her contributions have helped establish SABR as a standard of care, bridging the gap between technical dosimetric precision and meaningful patient-reported outcomes.

Research Focus

Key Achievements

Top Papers

1. 1
   Long-term quality of life in early-stage non-small cell lung cancer patients treated with robotic stereotactic ablative radiation therapy

   24 citations · 2015
2. 2
   Accuracy of Breath-hold CT in Treatment Planning for Lung Stereotactic Ablative Radiotherapy

   2 citations · 2014

Key Collaborators

Contact & Links