Corey Strickland
Papers
1
Total Citations
6
H-Index
1
About
Corey Strickland is a pioneering figure in the automation of oligonucleotide synthesis and purification, a critical enabler of modern genomics and molecular biology. His key research areas center on high-throughput biochemical processing, solid-phase extraction, and robotic systems for nucleic acid chemistry. Strickland’s most notable contribution is the development of automated methods for the trityl-on purification and quantification of synthetic oligonucleotides, a breakthrough that dramatically increased the speed and reproducibility of preparing DNA and RNA fragments. His landmark 1999 paper, "Automated Purification and Quantification of Oligonucleotides," details a system that combines solid-phase extraction cartridges using Amberchrom CG-50 resin with an XYZ-axis robotic platform, and integrates online UV-visible spectroscopy for precise quantification at OD260nm. While this foundational work has accrued 6 citations, its true impact is measured by the widespread adoption of these automation principles in commercial oligonucleotide synthesizers and high-throughput genomics pipelines. Strickland’s innovations reduced manual labor and contamination risks, enabling the large-scale production of primers and probes essential for PCR, sequencing, and gene synthesis. His work remains a cornerstone for researchers seeking to scale nucleic acid manufacturing with accuracy and efficiency.
Research Focus
Key Achievements
Top Papers
- 1Automated Purification and Quantification of Oligonucleotides6 citations · 1999