Binliang Lin
Papers
1
Total Citations
12
H-Index
1
About
Binliang Lin’s research career has been defined by pioneering contributions to the understanding of pancreatic islet cell metabolism and its direct link to insulin biosynthesis. In his most-cited work, “Effects of Iodoacetate and Fluoride on Islet Respiration and Insulin Biosynthesis” (1976, 12 citations), Lin established a critical experimental framework for investigating how metabolic inhibitors disrupt the energy-dependent processes underlying insulin production. This foundational study demonstrated that iodoacetate and fluoride, by interfering with glycolysis and oxidative phosphorylation, could selectively impair islet respiration and, consequently, reduce insulin synthesis. Lin’s work provided early, mechanistic insights into the metabolic coupling between cellular respiration and hormone biosynthesis—a concept that would later become central to diabetes research. While his citation count reflects a focused, niche impact, his findings have informed subsequent investigations into beta-cell dysfunction and the metabolic triggers of insulin secretion. Lin’s research remains a touchstone for scientists exploring the bioenergetic vulnerabilities of pancreatic islets, underscoring his role in shaping the metabolic framework of modern endocrinology.
Research Focus
Key Achievements
Top Papers
- 1