MP2-06 CAN PROGNOSTIC NUTRITIONAL INDEX (PNI) PREDICT OUTCOMES AFTER ROBOT-ASSISTED RADICAL CYSTECTOMY?

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Evidence-based Medicine & Outcomes II1 Apr 2014MP2-06 CAN PROGNOSTIC NUTRITIONAL INDEX (PNI) PREDICT OUTCOMES AFTER ROBOT-ASSISTED RADICAL CYSTECTOMY? Mohammed Tawfeeq, Syed Johar Raza, Katherine Szymanski, Ali Al-Daghmin, Erinn Field, Zayn Mehboob, Andrew Syposs, Zhengyu Yang, Katy Wang, Gregory Wilding, and Khurshid Guru Mohammed TawfeeqMohammed Tawfeeq More articles by this author , Syed Johar RazaSyed Johar Raza More articles by this author , Katherine SzymanskiKatherine Szymanski More articles by this author , Ali Al-DaghminAli Al-Daghmin More articles by this author , Erinn FieldErinn Field More articles by this author , Zayn MehboobZayn Mehboob More articles by this author , Andrew SypossAndrew Syposs More articles by this author , Zhengyu YangZhengyu Yang More articles by this author , Katy WangKaty Wang More articles by this author , Gregory WildingGregory Wilding More articles by this author , and Khurshid GuruKhurshid Guru More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.164AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Nutritional status plays an important role in the outcomes of malignant diseases. Prognostic Nutritional Index (PNI) has been successfully used to predict outcomes in colo-rectal cancer, however no reports exist for its use in bladder cancer. This study aims to determine if PNI can predict the operative and oncological outcomes following robot-assisted radical cystectomy (RARC) in bladder cancer. METHODS A retrospective comparative analysis of patients undergoing RARC was performed. PNI was measured using the serum albumin and absolute lymphocyte counts (PNI= Albumin x 10 + LC x 0.005). Based on the preoperative PNI values, all patients were divided into 2 groups, (PNI > 50 - normal and < 50 - malnutrition). Both groups were compared in terms of their baseline (demographic and clinical) outcomes. Oncologic and peri-operative outcomes included complications, hospitalization (stay and readmissions) were evaluated. Multivariable analysis was performed to determine if PNI score affected the operative or oncological outcomes. RESULTS 203 patients had their PNI determined using the mentioned formula. Mean age was 68.3 years (+/-10.8). Seventy two patients were categorized as PNI > 50, while 131 belonged to PNI <50. Both groups were comparable in age, gender, BMI, duration of surgery, estimated blood loss and pathological T stage. The mean ASA score was significantly lower in the PNI > 50 group. (2.4 vs 2.6, p= 0.015). In terms of peri-operative outcomes, the PNI > 50 group was associated with shorter hospital stay (1.5 vs 2.6 days, p=<.001), however 90 day complications and readmissions were not significantly different in both groups. Although both local and metastatic recurrence was noted more in PNI > 50 group, but this difference was not statistically significant. On the KM curve, the PNI> 50 group demonstrated a better metastasis free survival, than the PNI<50 group (p=0.03). CONCLUSIONS PNI> 50 is associated with shorter hospital stay and a better metastasis free survival following RARC. Multi-institutional studies will help better understand its use in comparing outcomes for radical cystectomy between minimally invasive and open approach. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e27 Advertisement Copyright & Permissions© 2014Metrics Author Information Mohammed Tawfeeq More articles by this author Syed Johar Raza More articles by this author Katherine Szymanski More articles by this author Ali Al-Daghmin More articles by this author Erinn Field More articles by this author Zayn Mehboob More articles by this author Andrew Syposs More articles by this author Zhengyu Yang More articles by this author Katy Wang More articles by this author Gregory Wi