Anaesthetic management of a patient with glucose-6-phosphate dehydrogenase deficiency undergoing robotic-assisted laparoscopic radical prostatectomy

Abstract

Glucose-6-phosphate dehydrogenase deficient patients may develop acute haemolysis after exposure to the oxidative stress of surgery, and certain anaesthetic or analgesic agents. The steep Trendelenburg position, pneumoperitoneum, and associated extreme hemodynamic changes in robotic surgery add on to oxidative stress. Here, we present a 68-year-old Glucose-6-phosphate dehydrogenase deficient patient who uneventfully underwent robotic-assisted laparoscopic radical prostatectomy focussing on avoidance of drugs predisposing haemolysis, minimising surgical stress, providing adequate anxiolysis, analgesia, stable haemodynamics and depth of anaesthesia that is unique to robotic surgery.