Optical Trapping, Cell Manipulation, And Robotics

Abstract

A new type of analytical and preparative cytometric instrument was developed. The instrument combines image analysis and machine vision with single cell and chromosome manipulation by means of optical trapping. A proof-of-principle instrument, OCAM, has the ability to locate and analyze biological particles inside an enclosed manipulation chamber, as well as the ability to move and position particles according to preprogrammed protocols. Preliminary results and potential biological applications of such a microrobot are discussed.