Zhibo Liu
Papers
1
Total Citations
42
H-Index
1
About
Zhibo Liu is a leading figure in radiochemistry and molecular imaging, whose work has significantly advanced the field of positron emission tomography (PET) tracer development. His research focuses on innovative methods for the rapid and efficient radiolabeling of biomolecules, particularly using fluorine-18, a key isotope for PET imaging. Liu's major contribution is the development of a groundbreaking, one-step aqueous <sup>18</sup>F-labeling technique that leverages aryltrifluoroborate bioconjugates. This method, detailed in his highly cited 2012 paper (42 citations), overcomes the long-standing challenge of producing radiotracers with high specific activity under mild, biocompatible conditions. By enabling the direct capture of aqueous fluoride ions at buffered pH 2-3, his work dramatically simplifies the synthesis of PET probes, making them more accessible for clinical and research applications. This innovation has profound implications for cancer diagnosis, neurology, and drug development, allowing for the non-invasive visualization of biological processes. Liu's contributions have established him as a key innovator in the quest for more effective and practical molecular imaging agents.
Research Focus
Key Achievements
Top Papers
- 1