Papers
3
Total Citations
109
H-Index
3
About
Zheng Ouyang is a bioanalytical scientist whose research has made significant contributions to the field of pharmaceutical sample preparation and liquid chromatography-tandem mass spectrometry (LC–MS/MS) methodology. Ouyang's work has focused primarily on developing and optimizing techniques for biological sample purification and processing, with a particular emphasis on automating workflows to improve efficiency and reliability in regulated bioanalysis. Ouyang's most influential contribution, cited 79 times, compared manual and automated approaches to plasma sample purification, providing the field with critical benchmarking data for liquid–liquid extraction and solid-phase extraction methods. This work helped standardize best practices in pharmaceutical bioanalysis. Building on this foundation, Ouyang later developed an innovative Excel-based robotic sample preparation program to automate biological sample dilution — a notoriously time-consuming bottleneck in bioanalytical workflows — earning an additional 23 citations. More recently, Ouyang advanced the field further with a streamlined, fully automated LC–MS/MS workflow incorporating cap-piercing direct sampling and evaporation-free solid phase extraction, reducing manual intervention and potential sources of error. Collectively, Ouyang's body of work reflects a consistent drive toward greater automation, accuracy, and practicality in bioanalytical chemistry, providing researchers and pharmaceutical scientists with tools that meaningfully accelerate drug development timelines.
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