Yongxin Han

Papers

Total Citations

H-Index

About

Yongxin Han is a researcher whose work centers on the molecular mechanisms of apoptosis, with a particular focus on caspase-3 activity and its role in programmed cell death. Han’s major contribution lies in developing precise methodologies to quantify caspase-3 inhibition and correlate it with apoptotic markers, as demonstrated in their most-cited paper, "Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay" (2005). This study, which has garnered 3 citations, introduced a novel ELISA-based approach that allowed for the direct measurement of active caspase-3 levels, enabling researchers to establish a quantitative link between enzyme inhibition and downstream apoptotic events. By providing a reliable tool for assessing caspase-3 activity in cellular models, Han’s work has implications for understanding neurodegenerative diseases and cancer, where apoptosis dysregulation is key. Though their citation count is modest, the specificity and methodological rigor of their research have made it a valuable reference for scientists studying cell death pathways. Han’s contributions exemplify how focused, technique-driven studies can advance fundamental knowledge in cell biology.